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Okay, the AI stuff is cool, but that "Containerization framework" mention is kinda huge, right? I mean, native Linux container support on Mac could be a game-changer for my whole workflow, maybe even making Docker less of a headache.

Here's the paper: https://www.nature.com/articles/s41467-025-60001-2

To be clear: they deliver the HIV TAT protein which activates latent cells to transcribe HIV (ultimately possibly producing viable HIV virions).

Activating-to-kill has been pursued with other agents, but none have proven effective at depleting the reservoir. (The latent reservoir requires HIV anti-retroviral therapy to be lifelong, making one of the top three most expensive diseases in the US).

This may be more of a proof for the method, of encapsulating a fragile mRNA in a protective lipid layer, but one which will be incorporated into cells. I'd expect it to be used outside attempts to cure HIV (having consumed some HIV funding).


The MLC team got that working back in March: https://github.com/mlc-ai/web-stable-diffusion

Even more impressively, they followed up with support for several Large Language Models: https://webllm.mlc.ai/


They have 400k of stock, though. It's common for a company not to keep a lot of cash around and borrow as needed against stock, which I would guess they are doing as they have 200k+ of creditors.

So, my guess is that they used income to build up stock of their clevo lines in order to reduce delivery times and increase their market to delivery sensitive customers, and now they are leveraging that to invest in the custom versions. If they are doing their own sw and there product is an integration of off the shelf parts, maybe it's doable.

Edited to add:

Actually I misread the statement, they have 200k falling due in a year and a further 700k of debt. So that's nearly 1M of investment, which seems easily enough to do this development, given it's much less complex than the framework devices.


> I struggled a lot with deciding to buy a cube. It felt wrong to spend so much money on a featureless hunk of metal.

When I bought my cube, I used it as an exercise to fight back against my frugality.

But it wasn't meant to be: it was delivered to the wrong address and I received a full refund.

Then my neighbor delivered it to me.


$9,000 for a 1cm cube. That's "winning the lotto impulse purchase" level for me.

If you want to echo the last paragraph of the article, the system also doesn’t know when to stop.

Which leads to a simple improvement: teach the model when to stop, what sections to remove. There’s already great ML-based summary engines, and systems able to answer questions from descriptions.


If that's too simple for you, you may have fun with the strlen implementation in glibc:

https://sourceware.org/git/?p=glibc.git;a=blob_plain;f=strin...


Bah, we have this in Greek also. How "cultured" one is can be seen in their speech. In Greek it's not speaking with big words ("exacerbate" vs. "make worse") but how many old Greek words one uses. For instance, pretentious twats that fancy themselves to be educated above the common folk will use words that sound like something Solon would have said to his slaves or Konstantine II to his horse.

Then there's the matter of diacritics. Hellenistic Greek used to have a panoply of diacritics, of two kinds, one kind to change the pitch of vowels and one to indicate a soft or hard sound (occasionally used on consontants, particularly rho, ρ). These could even be combined together to make Greek text something that looked a little like a vim regex. With time, Greek pronounciation lost its pitch accent and the diacritics became irrelevant to spoken Greek. Yet they were kept on in written text until the early 1980's when they were finally abolished from the school curriculum so most people today don't know how to use those. Unless of course they make a point of writing in the "polytonic" system that includes the diacritics, which they will invariably tell you is because "that's more correct". In truth, it's not more correct, it's anachronistic and archaic, but it marks the person out as someone who is e r u d i t e.

So it's not just English, sorry to say. In fact it's easier to see how you'd have classism in the UK, which is, after all, a United Kingdom, with a monarch and hereditary (?) lords and all. In a place like Greece it's harder to justify because there everyone is basically middle class, with small variations- and we booted our last king out in the 1970's. So here it's even more pathetic when people put on airs. In the UK it's more a political thing, they're trying to put you in your place. But in the UK, it's not the language that's the problem, it's that society is rigidly stratified and language is only the symptom of the awful inequalities.

______________

[1] Wikipedia has the works: https://en.wikipedia.org/wiki/Greek_diacritics


It’s worse....

It’s Linux only so no Mac, Windows or WSL.

No support what so ever for APUs which means if you have a laptop without a dedicated GPU you’re out of luck (tho discrete mobile GPUs aren’t officially supported either and often do not work).

They’ve not only haven’t been supporting any of their consumer based R“we promise it’s not GCN this time”DNA GPUs, but since December last year (2020) they’ve dropped support for all pre-Vega GCN cards which means that Polaris (400/500 series) which is not only the most prolific of AMD GPUs that have been released in the past 5 years or so but also the most affordable ones are no longer supported.

That’s on top of all the technical and architectural software issues that plague the framework.


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