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How can they pass it on when they don't have the defect any more?


Gene editing is still pretty crude in terms of delivery.

Just because you can hit some germ-line cells in the liver, for example, doesn’t imply you’ll have good penetration into the reproductive organs.

We can’t zap people and change all their DNA at once, unless we can intervene at the point it’s just a few cells.


The DNA was only edited in the liver. But by the time this baby grows up and starts a family, we'll probably be able to fix that, too.


That's a bold claim. The baby is 9 month old, there are many things that can still go wrong with this experimental treatment.

Hopefully not, but even then no one can say what progress will make science in the next 25 years.

Back in the 50's people thought we would be driving in flying car in 2000.


Four years ago highly-upvoted /r/SanFrancisco comments said self-driving taxis were decades away: https://old.reddit.com/r/sanfrancisco/comments/nbjsij/real_r...


12 upvotes...

You can't compare that to gene-editing treatments, that's two completely different level.

Self driving car were always almost feasible, 20 years ago top gear made cars you could drive with controller like kids do with toy cars. We already had camera and computer, it was just a matter of raw CPU performance and software development..


we have all the CPU performance we need and all software development we need and self-driving cars are driving around in roughly 0.00785% of world’s cities :)


If by "they" you mean their gametes, those were not edited. Only a component of their corporal shell was modified.


It only affects some cells, not the whole body.


> I'm thinking the best approach if I had time/money would be to develop a better query language that is close enough to SQL for people to learn, but then also translates back down to SQL

Have a look at EdgeQL, the query language that powers edgedb.


Too many folks' livelihoods depend on it at this point. The other side of the same coin is the gaslighting that you can't build anything sufficiently complex without react. If you did build it without react, it obviously wasn't sufficiently complex.


Quora and reddit too


Yes you can: https://wt5hp.csb.app/ (implemented in pure CSS, with some JS to demonstrate that it works)


Thanks! And darn, I forgot about css grid. I think this example wasn't possible with flexbox a few years ago.


> "As they stare into the mirror and perceive only the myth of their exceptionalism, Americans remain almost bizarrely incapable of seeing what has actually become of their country."


I think you've misread; the referenced tweet is about dismay over the anger that got the colleague fired.


France also has online.net (now Scaleway?) which I haven't used recently but was very good and reliable for me 3 years ago. Been using Hetzner ever since, which has set the new bar.


Try zustand!



Yeah that's way more readable and intuitive than anything that came before (that I'm aware of)!


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