It also says "Several ongoing trials have
been addressing the early use of CQ, in which the anti-inflammatory properties could be more
helpful. That information is urgently needed." and also " Unfortunately, this study’s randomization, probably due to the low sample size, assigned older patients with heart disease to the high dosage arm." Uh-oh.
TL;DR of the paper: if we give as much CQ as the Chinese recommend, people seem to have heart related side effects, so we had to stop treating them with the drug. And if we select older patients with heart disease for the high dosage arm, they tend to experience more side effects.
