The Fountain was really interesting in this regard, as it had the main character floating in a giant orb surrounding the Tree of Life. Completely different from the typical spaceship aesthetic. IIRC the space background was all microphotography, not CGI.

https://duckduckgo.com/?q=the+fountain+movie+space+ship&t=os...

https://www.youtube.com/watch?v=sdmPrsKV0Kg