Are people on college campuses generally clamoring to see a standup routine from Jerry Seinfeld? As the article points out, he's 66 years old and his humor is self-described as "observational". Maybe today's college students just don't connect to the observations of someone two generations older than them?
But why perform for an audience full of people who won't enjoy it? In my experience, performances hosted at colleges overwhelmingly attract audiences of students. It's nobody's fault that his humor doesn't land with that audience, but it is his fault that he's blaming the students for it.