> A number of studies assessing adherence to diabetes medications in patients with type 2 diabetes have reported that metformin has the lowest adherence rates when compared with other OAAs.
If it's due to its ability to reduce blood glucose levels, then berberine may be another way to get a similar effect.
Berberine stimulates glucose transport through a mechanism distinct from insulin
https://www.sciencedirect.com/science/article/pii/S002604950...
Efficacy of Berberine in Patients with Type 2 Diabetes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410097/
It also lowers cholesterol
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
https://www.nature.com/articles/nm1135
But pure berberine is not absorbed very well in the intestines, so you need to buy a good formation for it.
Enhancement of sodium caprate on intestine absorption and antidiabetic action of berberine
https://www.ncbi.nlm.nih.gov/pubmed/20237966/
Amorphous solid dispersion of berberine with absorption enhancer demonstrates a remarkable hypoglycemic effect via improving its bioavailability
https://pubmed.ncbi.nlm.nih.gov/24607213/
The best thing might be to cook with barberries:
https://thecaspianchef.com/2020/01/18/zereshk-polo-saffron-b...
> A number of studies assessing adherence to diabetes medications in patients with type 2 diabetes have reported that metformin has the lowest adherence rates when compared with other OAAs.