It's a true statement; LD_PRELOAD cannot be used with statically linked binaries. You can "fiddle" in other ways, but not by using the LD_PRELOAD attack vector (although personally I wouldn't call it an "attack vector", although in some cases it could be where you can upload a malicious file and control the environment of another program somehow, or something along those lines).
>Which is unambiguously not the case, they merely slow it down by a small margin.
When you are using shared libaries, it is fairly trivial to hook into the library calls and replace them with whatever you want. When you are using static libraries, the linker and optimizer could for example inline the machine code directly in the application code. What tools do you have to do similar tricks with statically compiled binaries?
Which is unambiguously not the case, they merely slow it down by a small margin.