I've been going down the rabbit hole of using all physically modeled synths instead of sample based VSTs so that I can fully take advantage of MPE controls instead of trying to get samples to be expressive though arcane incantations of key twidding in Kontakt. I think it's probably the best option for doing things in a DAW right now, unfortunately.
Would love to find out more about what you're doing here. Not all physical modelling options allow dynamic retuning. Also, which software will allow a double reed like the mijwiz. We really need modartt to crack the remaining instrument classes :) if you're open to chat, do you mind dropping an email to the address in my profile?