For some complex peripherals (especially wireless) this may be the case, but in my experience it's often much easier to write small abstractions for what you need in the mode you need it in (for serial, timers, IO, DMA, ...) than relying on manufacturer SDKs, which are often so poorly documented that you need the reference manual anyways to understand the peripheral to then understand the abstraction, which is often much more complex to use than it needs to be for my use cases. With abstractions in Rust or, for something quickly thrown together, in uPython you're at least getting "you're holding it wrong errors".

Interfacing with the peripheral registers themselves is also a bit simpler with Rust in my experience, as a proper .svd already contains bitfield setups with enums and R/RW/W1 information to at least set the bits you want instead of the Macro-Hell in C some manufacturers throw at you.