It took a while to get used to vertical tabs but once that took, I have moved completely to Zen. It was good to see it move from alpha to beta recently.
Too bad they removed the ability to open the vertical tabs side bar on hover, that was a critical feature that caused me to go back to Firefox proper. I'll go back to Zen once they add it but to be honest, I'm not too sure what extra value Zen would bring me.
I am talking about this feature [0], it should have the option to show all the tab icons and expand on hover, not hide the side bar entirely. The creator said this was being dropped due to maintenance concerns, and I haven't seen a community solution like they said yet.