There was some discussion awhile back about Intel potentially fabbing ARM chips (or any other custom non-x86 chip) as a viable business in the future. I don’t know how serious they were but it sounded plausible when you think about how important it is to have an American leading edge fab, independent of the market future of the x86 ISA.
Basically what would it take for Intel to still have Apple as a customer even if Apple made their own ARM designs…