“Mediating alertness”, as in more available norepinephrine increases or deceases how alert you are?
From my experience while awake, I would assume decreases. While it’s yet to have a huge impact on my ADHD, it’s has had a noticeable impact on reducing my self-doubt and hesitance to speak up. But I’m not sure how to unify that with it reducing the quality of my sleep.
Maybe, since I’m taking it in the AM it’s wearing off at night, and thus my level of alertness in the middle of the night is being heightened. That would line up with antidotal reports I’ve read of people saying they had less sleep disruptions when they took it at night. Something I’m planning to try moving to.
It’s also possible it takes take to reach a steady state (I’ve only been taking it two weeks)
