I've been running the Xfce spin of Fedora for the last year, and it is the most stable OS I have since forever.

For the few programs that really need Windows, I use Qemu/KVM with Virt-Manager and Samba for sharing files.

I wish to keep using this setup, I just hope buying hardware with good Linux support in the future does not become too difficult. I fear moving away from x86 will make things harder.