I used to be a big fan of Homebrew but switch to Nix about 2 years ago. For the most part, it works great with home manager for me. Many tools can be installed with breeze just like breeze albeit a bit quicker. The critical thing for me is that Nix doesn't polute my Mac environment like Brew does. But, I admit that this is just for tools. For dev environment I usually just fall back to the language specific methods like cargo, uv or npm.