I used to use Home Assistant via Docker, but I've since switched to Proxmox with HAOS in a VM and a second Debian VM for everything else. My main reason for this is that it seems like the more supported scenario. For example, when the Voice Assistant stuff first came out the setup was only really documented via HAOS add-ons. I managed to get it working with standalone Docker containers but it was a pain to figure out. It really is simpler to just use HAOS IMO.