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> If not, what fundamental building blocks are missing to get there

If I were to guess, the missing building block is the ability to abstract - which is the ability to create a symbol to represent something. Concrete example of abstraction is seen in the axioms of lambda calculus. 1) ability to posit a variable, 2) ability to define a function using said variable, and 3) the ability to apply functions to things. Abstraction arises from a process in the brain which we have not understood yet and could be outside of computation as we know it per [1]

[1] https://www.amazon.com/Emperors-New-Mind-Concerning-Computer...



No. It's not microtubules. Enough with the g-darn microtubules already. https://www.biorxiv.org/content/10.1101/712794v1

"We used an antimicrotubular agent (parbendazole) and disrupted microtubular dynamics in paramecium to see if microtubules are an integral part of information storage and processing in paramecium’s learning process. We observed that a partial allosteric modulator of GABA (midazolam) could disrupt the learning process in paramecium, but the antimicrotubular agent could not. Therefore, our results suggest that microtubules are probably not vital for the learning behavior in P. caudatum. Consequently, our results call for a further revisitation of the microtubular information processing hypothesis."




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