Like back when CRTs were mainstream you'd have those computer labs with monitors set to 60-85Hz and most people wouldn't notice, but some would. I definitely did, I couldn't stand looking at a CRT set to less than 100 Hz for more than an hour.
Absolutely, I also had massive issues with them, ending with red eyes and headaches within an hour of use. Getting my first LED monitor (with a CCFL backlight) was out of this world.
