For a first run-through, I'd recommend the "Zero Rando" edition of the [Deus Ex Randomizer](https://github.com/Die4Ever/deus-ex-randomizer/) mod, since that's strictly limited to quality-of-life and bug fixes. If you're playing on a Steam Deck or with a controller, it integrates a radial menu for augmentations, which will help a ton when mapping the mouse-and-keyboard controls onto a gamepad.