Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

Isn’t this a largely solved problem after Alphafold?


Should an entry in a field preclude other ones. I encourage you to apply reductio-ad-absurdum here. Should Pepsi exist if Coke does? Should C exist if Fortran does?


Maybe they've been working on it, but got scooped?


I don't think that's the case. The numbers in the paper suggest ~92% of the training data comes from pre-existing AI models, including AlphaFold, and they claim things like:

> We largely adopt the data pipeline implemented in Boltz-11 1https://github.com/jwohlwend/boltz (Wohlwend et al., 2024), which is an open-source replication of AlphaFold3

I believe the story here is largely that they simplified the architecture and scaled it to 3B parameters while maintaining leading results.




Consider applying for YC's Winter 2026 batch! Applications are open till Nov 10

Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: