Profiles for the typical Work/Personal separation with their own bookmarks, extensions, password manager accounts etc……
Then I use containers for isolating sensitive accounts within those profiles (bank, work Google Drive, etc).
I also use temporary containers to make it easier to be logged into the same site with multiple accounts at the same time between tabs - like admin and user accounts for our company’s app - which also make it easier to clear sessions and data.
The growing consensus seems to be: containers are what services you want to separate from each other (cross-service tracking cookies, etc) and profiles are what services you want to separate for yourself (workflows/projects/work versus fun, etc).
