There are some tradeoffs in the other direction. Digital neurons can have advantages that biological neurons do not.

For example, if biology had a "choice" I am fairly confident that it would have elected to not have leaky charge carriers or relatively high latency between elements. Roughly 20% of our brain exists simply to slow down and compensate for the other 80%.

I don't know that eliminating these caveats is sufficient to overcome all the downsides, but I also don't think we've tried very hard to build experiments that directly target this kind of thinking. Most of our digital neurons today are of an extremely reductive variety. At a minimum, I think we need recurrence over a time domain. The current paradigm (GPU-bound) is highly allergic to a causal flow of events over time (i.e., branching control flows).